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Biliary endoscopic sphincterotomy is a minimally invasive procedure performed during endoscopy to facilitate access to the duodenum and the common bile duct. This technique is primarily used to treat conditions such as choledocholithiasis (the presence of stones in the common bile duct), cholangitis (infection of the bile duct), and to aid in biliary drainage. The procedure involves the insertion of an endoscope through the mouth, down the esophagus, and into the duodenum, where the ampulla of Vater is located; this is the area where the bile duct and pancreatic duct open. Once the endoscope is positioned, a specialized instrument called a sphincterotome is utilized to make an incision in the sphincter of Oddi, the muscular valve that controls the flow of bile and pancreatic juices into the duodenum. This incision allows for the extraction of bile duct stones and facilitates the placement of drainage devices, such as biliary stents, if necessary. The procedure is typically performed under sedation and can be done on an outpatient basis, making it a preferred option for many patients needing interventions on their biliary systems. Risks associated with biliary endoscopic sphincterotomy include pancreatitis, bleeding, perforation of the duodenum, and infections, but these complications are relatively rare. Post-procedural care may include monitoring for signs of these complications and ensuring that the patient is managing any discomfort appropriately. The success rate of the procedure is quite high, particularly when performed by skilled endoscopists, and it significantly reduces the need for more invasive surgical options. Patients are usually able to resume normal activities within a few days, although some may experience mild abdominal pain or diarrhea as the body adjusts. Overall, biliary endoscopic sphincterotomy represents an essential advancement in endoscopic techniques, providing a less invasive alternative to surgery and improving the quality of care for individuals with biliary disorders.